Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

ABSTRACT Understanding the interplay between antibiotic resistance and bacterial fitness and virulence is essential to guide individual treatments and improve global antibiotic policies. A paradigmatic example of a resistance mechanism is the intrinsic inducible chromosomal β-lactamase AmpC from mul...

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Bibliographic Details
Main Authors: Marcelo Pérez-Gallego, Gabriel Torrens, Jane Castillo-Vera, Bartolomé Moya, Laura Zamorano, Gabriel Cabot, Kjell Hultenby, Sebastián Albertí, Peter Mellroth, Birgitta Henriques-Normark, Staffan Normark, Antonio Oliver, Carlos Juan
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01783-16