Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data
Spatially resolved transcriptomics is a relatively new technique that maps transcriptional information within a tissue. Here the authors present MIST, which detects molecular regions from spatially resolved transcriptomics and denoises the missing gene expression values by region-specific imputation...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34567-0 |