Phenotyping EMT and MET cellular states in lung cancer patient liquid biopsies at a personalized level using mass cytometry

Phenotyping EMT and MET cellular states in lung cancer patient liquid biopsies at a personalized level using mass cytometry

Abstract Malignant pleural effusions (MPEs) can be utilized as liquid biopsy for phenotyping malignant cells and for precision immunotherapy, yet MPEs are inadequately studied at the single-cell proteomic level. Here we leverage mass cytometry to interrogate immune and epithelial cellular profiles o...

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Bibliographic Details
Main Authors: Loukia G. Karacosta, Danny Pancirer, Jordan S. Preiss, Jalen A. Benson, Winston Trope, Joseph B. Shrager, Arthur Wai Sung, Joel W. Neal, Sean C. Bendall, Heather Wakelee, Sylvia K. Plevritis
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46458-5

Internet

https://doi.org/10.1038/s41598-023-46458-5

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