Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment

Current antiplatelet drugs for the treatment of arterial thrombosis often coincide with increased bleeding risk. Several tyrosine kinase inhibitors (TKIs) for cancer treatment inhibit platelet function, with minor reported bleeding symptoms. The aim of this study was to compare the antiplatelet prop...

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Bibliographic Details
Main Authors: Bibian M. E. Tullemans, Alicia Veninga, Delia I. Fernandez, Maureen J. B. Aarts, Johannes A. Eble, Paola E. J. van der Meijden, Johan W. M. Heemskerk, Marijke J. E. Kuijpers
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
platelet activation
aggregation
bleeding
thrombus formation
tyrosine kinase inhibitors
antiplatelet treatment
Online Access:https://www.mdpi.com/1422-0067/22/20/11199

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https://www.mdpi.com/1422-0067/22/20/11199

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