Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.

Little is known about extrinsic signals required for the advancement of motor neuron (MN) axons, which extend over long distances in the periphery to form precise connections with target muscles. Here we present that Rnf165 (Arkadia-like; Arkadia2; Ark2C) is expressed specifically in the nervous sys...

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Bibliographic Details
Main Authors: Claire E Kelly, Efstathia Thymiakou, James E Dixon, Shinya Tanaka, Jonathan Godwin, Vasso Episkopou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23610558/pdf/?tool=EBI