Extracellular vesicles aggravate NASH progression by promoting the activation of M1 macrophages

Objective To explore the effect of extracellular vesicles (EVs) secreted by steatotic hepatocytes on the activation of macrophages. Methods The nonalcoholic steatohepatitis (NASH) model was established by feeding SD rats with high-fat and high-cholesterol diet (HFHCD). Hepatic lesions of rats were o...

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Bibliographic Details
Main Author: Wan Zhiping, Yang Xiaoan, Deng Hong
Format: Article
Language:zho
Published: Editorial Office of Journal of New Medicine 2022-07-01
Series:Xin yixue
Subjects:
Online Access:https://www.xinyixue.cn/fileup/0253-9802/PDF/1659601313003-400597830.pdf