Decoding regulatory associations of G-quadruplex with epigenetic and transcriptomic functional components

G-quadruplex (G4) has been previously observed to be associated with gene expression. In this study, we performed integrative analysis on G4 multi-omics data from in-silicon prediction and ChIP-seq in human genome. Potential G4 sites were classified into three distinguished groups, such as one group...

Full description

Bibliographic Details
Main Authors: Shuyi Fang, Sheng Liu, Danzhou Yang, Lei Yang, Chang-Deng Hu, Jun Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.957023/full