NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis

NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis

Abstract Nucleotide-binding oligomerization domain 2 (NOD2) is an immune sensor crucial for eliciting the innate immune responses. Nevertheless, discrepancies exist regarding the effect of NOD2 on different types of cancer. This study aimed to investigate these function of NOD2 in melanoma and its u...

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Bibliographic Details
Main Authors: Fang Yun, Na Wu, Xiaojia Yi, Xuedan Zhang, Yu Feng, Qinxuan Ni, Yanlong Gai, Enjiang Li, Zhe Yang, Qiao Zhang, Buqing Sai, Yingmin Kuang, Yuechun Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07104-8

Internet

https://doi.org/10.1038/s41419-024-07104-8

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