Effects of antipsychotics, haloperidol and olanzapine, on the expression of apoptosis-related genes in mouse mHippoE-2 cells and rat hippocampus

Objective. Modified levels of pro- (caspase3, Bax) and anti-apoptotic (Bcl-2) regulatory proteins have been detected in certain brain areas of schizophrenic patients indicating a possible dysregulation of apoptosis. In the present study, effects of antipsychotics, haloperidol (HAL) and olanzapine (O...

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Bibliographic Details
Main Authors: Osacka Jana, Kiss Alexander, Bacova Zuzana, Tillinger Andrej
Format: Article
Language:English
Published: Sciendo 2023-01-01
Series:Endocrine Regulations
Subjects:
Online Access:https://doi.org/10.2478/enr-2023-0019