Strain engraftment competition and functional augmentation in a multi-donor fecal microbiota transplantation trial for obesity

Abstract Background Donor selection is an important factor influencing the engraftment and efficacy of fecal microbiota transplantation (FMT) for complex conditions associated with microbial dysbiosis. However, the degree, variation, and stability of strain engraftment have not yet been assessed in...

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Main Authors: Brooke C. Wilson, Tommi Vatanen, Thilini N. Jayasinghe, Karen S. W. Leong, José G. B. Derraik, Benjamin B. Albert, Valentina Chiavaroli, Darren M. Svirskis, Kathryn L. Beck, Cathryn A. Conlon, Yannan Jiang, William Schierding, David J. Holland, Wayne S. Cutfield, Justin M. O’Sullivan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Microbiome
Online Access:https://doi.org/10.1186/s40168-021-01060-7