Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression

Genetic studies of disease progression can be used to identify factors that may influence survival or prognosis, which may differ from factors that influence on disease susceptibility. Studies of disease progression feed directly into therapeutics for disease, whereas studies of incidence inform pre...

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Bibliographic Details
Main Authors: Ruth E. Mitchell, April E. Hartley, Venexia M. Walker, Apostolos Gkatzionis, James Yarmolinsky, Joshua A. Bell, Amanda H. W. Chong, Lavinia Paternoster, Kate Tilling, George Davey Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949638/?tool=EBI