Effects of HMGB1/TLR4 on secretion IL-10 and VEGF in human jaw bone-marrow mesenchymal stem cells

Abstract Objective: We aimed to investigate the regulatory effects of HMGB1/TLR4 signaling pathway on the expression of IL-10 and VEGF in human bone marrow mesenchymal stem cells. Methodology: Human JBMSCs were isolated and cultured. Then, HMGB1 was added into the JBMSCs culture medium, and the pr...

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Bibliographic Details
Main Authors: Jingjing Kong, Wei Cheng, Lianzhen Chang, Jingyi Yu, Ronglin Wang, Jianli Xie
Format: Article
Language:English
Published: University of São Paulo 2024-02-01
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100407&tlng=en