Preparation and Characterization of Spherical Amorphous Solid Dispersion with Amphotericin B

In the present study, new polymer microspheres of amphotericin B (AmB) were prepared by a spray drying technique using cyclodextrin polymers (Poly-CD) to improve the solubility and dissolution of AmB, to prevent in vivo toxic AmB aggregations. Formulations were characterized through scanning electro...

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Bibliographic Details
Main Authors: Lyes Mehenni, Malika Lahiani-Skiba, Guy Ladam, François Hallouard, Mohamed Skiba
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/10/4/235