IL‐36γ and IL‐36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell–Matrix Adhesion Network and Wnt Signaling

IL‐36γ and IL‐36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell–Matrix Adhesion Network and Wnt Signaling

Abstract Inflammatory bowel disease and colorectal cancer are associated with dysregulation of cytokine networks. However, it is challenging to target cytokines for effective intervention because of the overlapping functions and unpredictable interactions of cytokines in such diverse networks. Here,...

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Bibliographic Details
Main Authors: Wei Yang, Hong‐Peng Dong, Peng Wang, Zhi‐Gao Xu, Jiahuan Xian, Jiachen Chen, Hai Wu, Yang Lou, Dandan Lin, Bo Zhong
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Advanced Science
Subjects:
cell–matrix adhesion
colon cancer
IL‐36γ, IL‐36Ra
tumor microenvironment
Wnt signaling
Online Access:https://doi.org/10.1002/advs.202103035

Internet

https://doi.org/10.1002/advs.202103035

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