Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers

Smallpox, an epidemic disease caused by <i>Orthopoxvirus variola</i>, was eradicated worldwide through immunization. The immunization against smallpox was discontinued in 1980. However, incidences of monkeypox virus infection in humans have occurred sporadically, and there is also great...

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Bibliographic Details
Main Authors: Xiuling Gu, Yufan Zhang, Wei Jiang, Dongfang Wang, Jiao Lu, Guanglei Gu, Chengfeng Qin, Min Fang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/7/1084