Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers
Smallpox, an epidemic disease caused by <i>Orthopoxvirus variola</i>, was eradicated worldwide through immunization. The immunization against smallpox was discontinued in 1980. However, incidences of monkeypox virus infection in humans have occurred sporadically, and there is also great...
Main Authors: | Xiuling Gu, Yufan Zhang, Wei Jiang, Dongfang Wang, Jiao Lu, Guanglei Gu, Chengfeng Qin, Min Fang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/10/7/1084 |
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