Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport

Abstract Co-assembly of the multilayered coat protein complex II (COPII) with the Sar1 GTPase at subdomains of the endoplasmic reticulum (ER) enables secretory cargoes to be concentrated efficiently within nascent transport intermediates, which subsequently deliver their contents to ER-Golgi interme...

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Bibliographic Details
Main Authors: William Kasberg, Peter Luong, Kevin A. Swift, Anjon Audhya
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44002-7