Prim-O-glucosylcimifugin ameliorates aging-impaired endogenous tendon regeneration by rejuvenating senescent tendon stem/progenitor cells

Prim-O-glucosylcimifugin ameliorates aging-impaired endogenous tendon regeneration by rejuvenating senescent tendon stem/progenitor cells

Abstract Adult tendon stem/progenitor cells (TSPCs) are essential for tendon maintenance, regeneration, and repair, yet they become susceptible to senescence with age, impairing the self-healing capacity of tendons. In this study, we employ a recently developed deep-learning-based efficacy predictio...

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Bibliographic Details
Main Authors: Yu Wang, Shanshan Jin, Dan Luo, Danqing He, Min Yu, Lisha Zhu, Zixin Li, Liyuan Chen, Chengye Ding, Xiaolan Wu, Tianhao Wu, Weiran Huang, Xuelin Zhao, Meng Xu, Zhengwei Xie, Yan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-023-00288-3

Internet

https://doi.org/10.1038/s41413-023-00288-3

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