Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

Objective: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence of NAFLD, and thyroid hormone treatment is very pr...

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Bibliographic Details
Main Authors: Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
Liver
Steatosis
Thyroid
NAFLD
Deiodinase
NASH
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001113

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821001113

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