An optimized MNK1b aptamer, apMNKQ2, and its potential use as a therapeutic agent in breast cancer

An optimized MNK1b aptamer, apMNKQ2, and its potential use as a therapeutic agent in breast cancer

Breast cancer is the most commonly diagnosed and leading cause of cancer death among women worldwide. Mitogen-activated protein kinase-interacting kinases (MNKs) promote the expression of several oncogenic proteins and are overexpressed in several types of cancer. In human cells, there are four isof...

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Bibliographic Details
Main Authors: C. Pinto-Díez, R. Ferreras-Martín, R. Carrión-Marchante, J.I. Klett-Mingo, M. García-Hernández, M.I. Pérez-Morgado, S. Sacristán, M. Barragán, M. Seijo-Vila, I. Tundidor, S. Blasco-Benito, E. Pérez-Gómez, I. Gómez-Pinto, C. Sánchez, C. González, V.M. González, M.E. Martín
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Oligonucleotides: Therapies and Applications
aptamers
anti-tumor drug
cancer
metastasis
MNK
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122003018

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http://www.sciencedirect.com/science/article/pii/S2162253122003018

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