Decoding Oncofusions: Unveiling Mechanisms, Clinical Impact, and Prospects for Personalized Cancer Therapies

Cancer-associated gene fusions, also known as oncofusions, have emerged as influential drivers of oncogenesis across a diverse range of cancer types. These genetic events occur via chromosomal translocations, deletions, and inversions, leading to the fusion of previously separate genes. Due to the d...

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Bibliographic Details
Main Authors: Kari Salokas, Giovanna Dashi, Markku Varjosalo
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/14/3678