Negative spillover due to constraints on care delivery: a potential source of bias in pragmatic clinical trials

Abstract Background Pragmatic clinical trials evaluate the effectiveness of health interventions in real-world settings. Negative spillover can arise in a pragmatic trial if the study intervention affects how scarce resources are allocated across patients in the intervention and comparison groups. M...

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Bibliographic Details
Main Author: Sean Mann
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-024-08675-9