Negative spillover due to constraints on care delivery: a potential source of bias in pragmatic clinical trials
Abstract Background Pragmatic clinical trials evaluate the effectiveness of health interventions in real-world settings. Negative spillover can arise in a pragmatic trial if the study intervention affects how scarce resources are allocated across patients in the intervention and comparison groups. M...
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Trials |
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Online Access: | https://doi.org/10.1186/s13063-024-08675-9 |