Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis
Abstract Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human skin aging. Skin biopsies from healthy volu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-04-01
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| Series: | npj Aging and Mechanisms of Disease |
| Online Access: | https://doi.org/10.1038/s41514-021-00060-z |