Molecular targets that sensitize cancer to radiation killing: From the bench to the bedside

Molecular targets that sensitize cancer to radiation killing: From the bench to the bedside

Radiotherapy is a standard cytotoxic therapy against solid cancers. It uses ionizing radiation to kill tumor cells through damage to DNA, either directly or indirectly. Radioresistance is often associated with dysregulated DNA damage repair processes. Most radiosensitizers enhance radiation-mediated...

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Bibliographic Details
Main Authors: Sushmitha Sriramulu, Shivani Thoidingjam, Stephen L. Brown, Farzan Siddiqui, Benjamin Movsas, Shyam Nyati
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
BUB1
Cancer
DNA damage
DNA repair
Radiotherapy
Radiosensitization
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015153

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http://www.sciencedirect.com/science/article/pii/S0753332222015153

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