Nicotinic acetylcholine receptor density in cognitively intact subjects at an early stage of Parkinson’s disease

Nicotinic acetylcholine receptor density in cognitively intact subjects at an early stage of Parkinson’s disease

We investigated in vivo brain nicotinic acetylcholine receptor (nAChR) distribution in cognitively intact subjects with Parkinson's disease (PD) at an early stage of the disease. Fourteen patients and 13 healthy subjects were imaged with single photon emission computed tomography (SPECT) and th...

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Bibliographic Details
Main Authors: Ioannis Ugo eIsaias, Joerg eSpiegel, Joachim eBrumberg, Kelly P Cosgrove, Giorgio eMarotta, Naoya eOishi, Higuchi eTakahiro, Sebastian eKüsters, Markus eSchiller, Ulrich eDillmann, Chris eVan Dyck, Andreas eBuck, Ken eHerrmann, Susanne eSchloegl, Jens eVolkmann, Michael eLassmann, Klaus eFassbender, Reinhard eLorenz, Samuel eSamnick
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson Disease
nicotinic receptors
cognitive decline
5IA SPECT
dopamine acetylcholine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00213/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00213/full

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