Preferentially Expressed Antigen in Melanoma Is a Multifaceted Cancer Testis Antigen with Diverse Roles as a Biomarker and Therapeutic Target
Preferentially expressed antigen in melanoma (PRAME) is a cancer testis antigen (CTA) that is selectively expressed in certain somatic tissues, predominantly in the testis, and is overexpressed in various cancers. PRAME family proteins are leucine-rich repeat proteins that are localized in the nucle...
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Format: | Article |
Language: | English |
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MDPI AG
2023-08-01
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Series: | International Journal of Translational Medicine |
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Online Access: | https://www.mdpi.com/2673-8937/3/3/24 |