Preferentially Expressed Antigen in Melanoma Is a Multifaceted Cancer Testis Antigen with Diverse Roles as a Biomarker and Therapeutic Target

Preferentially expressed antigen in melanoma (PRAME) is a cancer testis antigen (CTA) that is selectively expressed in certain somatic tissues, predominantly in the testis, and is overexpressed in various cancers. PRAME family proteins are leucine-rich repeat proteins that are localized in the nucle...

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Bibliographic Details
Main Author: Mukulika Bose
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Translational Medicine
Subjects:
Online Access:https://www.mdpi.com/2673-8937/3/3/24