Gut Microbiota Abrogates Anti-α-Gal IgA Response in Lungs and Protects against Experimental <i>Aspergillus</i> Infection in Poultry

Gut Microbiota Abrogates Anti-α-Gal IgA Response in Lungs and Protects against Experimental <i>Aspergillus</i> Infection in Poultry

Naturally occurring human antibodies (Abs) of the isotypes IgM and IgG and reactive to the galactose-α-1,3-galactose (α-Gal) epitope are associated with protection against infectious diseases, caused by pathogens expressing the glycan. Gut microbiota bacteria expressing α-Gal regulate the immune res...

Full description

Bibliographic Details
Main Authors: Lourdes Mateos-Hernández, Veronica Risco-Castillo, Edgar Torres-Maravilla, Luis G. Bermúdez-Humarán, Pilar Alberdi, Adnan Hodžić, Angelica Hernández-Jarguin, Sabine Rakotobe, Clemence Galon, Elodie Devillers, Jose de la Fuente, Jacques Guillot, Alejandro Cabezas-Cruz
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Vaccines
Subjects:
alpha-Gal
microbiota
aspergillosis
<i>Aspergillus fumigatus</i>
granulomas
cross-protective immunity
Online Access:https://www.mdpi.com/2076-393X/8/2/285

Internet

https://www.mdpi.com/2076-393X/8/2/285

Similar Items