Gut Microbiota Abrogates Anti-α-Gal IgA Response in Lungs and Protects against Experimental <i>Aspergillus</i> Infection in Poultry

Gut Microbiota Abrogates Anti-α-Gal IgA Response in Lungs and Protects against Experimental <i>Aspergillus</i> Infection in Poultry

Naturally occurring human antibodies (Abs) of the isotypes IgM and IgG and reactive to the galactose-α-1,3-galactose (α-Gal) epitope are associated with protection against infectious diseases, caused by pathogens expressing the glycan. Gut microbiota bacteria expressing α-Gal regulate the immune res...

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Bibliographic Details
Main Authors:	Lourdes Mateos-Hernández, Veronica Risco-Castillo, Edgar Torres-Maravilla, Luis G. Bermúdez-Humarán, Pilar Alberdi, Adnan Hodžić, Angelica Hernández-Jarguin, Sabine Rakotobe, Clemence Galon, Elodie Devillers, Jose de la Fuente, Jacques Guillot, Alejandro Cabezas-Cruz
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Vaccines
Subjects:	alpha-Gal microbiota aspergillosis <i>Aspergillus fumigatus</i> granulomas cross-protective immunity
Online Access:	https://www.mdpi.com/2076-393X/8/2/285

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