Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline.

Environmental compounds including fungicides, plastics, pesticides, dioxin and hydrocarbons can promote the epigenetic transgenerational inheritance of adult-onset disease in future generation progeny following ancestral exposure during the critical period of fetal gonadal sex determination. This st...

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Bibliographic Details
Main Authors: Mohan Manikkam, M Muksitul Haque, Carlos Guerrero-Bosagna, Eric E Nilsson, Michael K Skinner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4109920?pdf=render