The Effect of Matrix Stiffness on Human Hepatocyte Migration and Function—An In Vitro Research

The extracellular matrix (ECM) regulates cellular function through the dynamic biomechanical and biochemical interplay between the resident cells and their microenvironment. Pathologically stiff ECM promotes phenotype changes in hepatocytes during liver fibrosis. To investigate the effect of ECM sti...

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Bibliographic Details
Main Authors: Tingting Xia, Runze Zhao, Fan Feng, Li Yang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/9/1903