IL-17 can be protective or deleterious in murine pneumococcal pneumonia.

Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection. The cytokine IL-17 protects against such colonization and vaccines that enhance IL-17 resp...

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Bibliographic Details
Main Authors: Neil D Ritchie, Ryan Ritchie, Hannah K Bayes, Tim J Mitchell, Tom J Evans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007099&type=printable