LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

Abstract Background Increasing evidence highlights the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the mechanism of AGAP2-AS1 in the occurrence and development of clear cell RCC (ccRCC) involving IGF2BP3/miR-9-5p/THBS2...

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Bibliographic Details
Main Authors: Peng Xu, Da-xiong Feng, Jun Wang, Yao-Dong Wang, Gang Xie, Bin Zhang, Xiao-Han Li, Jia-Wei Zeng, Jia-Fu Feng
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cancer Cell International
Subjects:
Renal cell carcinoma
N6-methyladenosine
Long non-coding RNA
AGAP2-AS1
IGF2BP3
miR-9-5p
Online Access:https://doi.org/10.1186/s12935-023-03173-5

Internet

https://doi.org/10.1186/s12935-023-03173-5

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