Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation

Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation

To reduce mucosal damage in the gastrointestinal tract caused by aspirin, we developed a dissolvable polymeric microneedle (MN) patch loaded with aspirin. Biodegradable polymers provide mechanical strength to the MNs. The MN tips punctured the cuticle of the skin and dissolved when in contact with t...

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Bibliographic Details
Main Authors: Baorui Wang, Suohui Zhang, Guozhong Yang, Zequan Zhou, Mengzhen Xing, Han Liu, Aguo Cheng, Yunhua Gao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Aspirin
Transdermal drug delivery
Polymeric microneedles
Hydrolysis
Antiplatelet aggregation
Online Access:http://www.sciencedirect.com/science/article/pii/S181808762300003X

Internet

http://www.sciencedirect.com/science/article/pii/S181808762300003X

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