The role of Crk adaptor proteins in T cell adhesion and migration

Crk adaptor proteins are key players in signal transduction from a variety of cell surface receptors. They are involved in early steps of lymphocyte activation through their SH2-mediated transient interaction with signal transducing effector molecules, such as Cbl, ZAP-70, CasL and STAT5. In additio...

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Bibliographic Details
Main Authors: Noah eIsakov, Alex eBraiman
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00509/full