A Direct Effect of Sex Hormones on Epithelial Barrier Function in Inflammatory Bowel Disease Models

Background: Pregnancy is often described as an immune-tolerant state, and a disease modulatory role for pregnancy on inflammatory bowel disease (IBD) has been suggested. The direct effect of estrogen and progesterone on the intestinal epithelial barrier is underexplored. We investigated the direct c...

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Bibliographic Details
Main Authors: Janine van der Giessen, C. Janneke van der Woude, Maikel P. Peppelenbosch, Gwenny M. Fuhler
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/3/261