Genetic variations in idiopathic pulmonary fibrosis and patient response to pirfenidone

Genetic variations in idiopathic pulmonary fibrosis and patient response to pirfenidone

Background: Genetic variations in Idiopathic Pulmonary Fibrosis (IPF) affect survival and outcomes. Current antifibrotic agents are managed based on the patient's reported side effects, although certain single nucleotide polymorphisms (SNPs) might alter treatment response and survival depending...

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Bibliographic Details
Main Authors: Aahd Kubbara, William H. Amundson, Adam Herman, Adam M. Lee, Jeffrey R. Bishop, Hyun Joo Kim
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Single nucleotide polymorphism
Idiopathic pulmonary fibrosis
Pirfenidone
Antifibrotic agents
Pharmacogenetics
Genotype
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402305781X

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http://www.sciencedirect.com/science/article/pii/S240584402305781X

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