Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model

Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model

Streptococcus pneumoniae is a major cause of invasive diseases such as pneumonia, meningitis, and sepsis, with high associated mortality. Our previous molecular evolutionary analysis revealed that the S. pneumoniae gene bgaA, encoding the enzyme β-galactosidase (BgaA), had a high proportion of codon...

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Bibliographic Details
Main Authors: Moe Takemura, Masaya Yamaguchi, Momoko Kobayashi, Tomoko Sumitomo, Yujiro Hirose, Daisuke Okuzaki, Masayuki Ono, Daisuke Motooka, Kana Goto, Masanobu Nakata, Narikazu Uzawa, Shigetada Kawabata
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Streptococcus pneumoniae
BgaA
coagulation
virulence factor
neutrophil
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.844000/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.844000/full

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