Space-related pharma-motifs for fast search of protein binding motifs and polypharmacological targets

<p>Abstract</p> <p>Background</p> <p>To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local bin...

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Bibliographic Details
Main Authors: Chiu Yi-Yuan, Lin Chun-Yu, Lin Chih-Ta, Hsu Kai-Cheng, Chang Li-Zen, Yang Jinn-Moon
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Genomics