Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth

Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth

Abstract Background Previous studies have identified genetic variants associated with bronchopulmonary dysplasia (BPD) in extremely preterm infants. However, findings with genome-wide significance have been rare, and not replicated. We hypothesized that whole exome sequencing (WES) of premature subj...

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Bibliographic Details
Main Authors: Aaron Hamvas, Rui Feng, Yingtao Bi, Fan Wang, Soumyaroop Bhattacharya, Jared Mereness, Madhurima Kaushal, C Michael Cotten, Philip L Ballard, Thomas J Mariani, PROP Investigators
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Genetics
Subjects:
Prematurity and respiratory outcomes program (PROP)
Bronchopulmonary dysplasia (BPD)
Online Access:http://link.springer.com/article/10.1186/s12863-018-0679-7

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http://link.springer.com/article/10.1186/s12863-018-0679-7

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