Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

Isoprenoid biosynthesis has a significant requirement for the co‐factor NADPH. Thus, increasing NADPH levels for enhancing isoprenoid yields in synthetic biology is critical. Previous efforts have focused on diverting flux into the pentose phosphate pathway or overproducing enzymes that generate NAD...

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Bibliographic Details
Main Authors: Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:FEBS Open Bio
Subjects:
glucose 6‐phosphate dehydrogenase
isoprenoids
NADPH
Saccharomyces cerevisiae
sclareol
ZWF1
Online Access:https://doi.org/10.1002/2211-5463.13755

Internet

https://doi.org/10.1002/2211-5463.13755

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