Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Type II DNA topoisomerases relax topological stress by transiently gating DNA passage in a controlled cut-and-reseal mechanism that affects both DNA strands. Therefore, they are essential to overcome topological problems associated with DNA metabolism. Their aberrant activity results in the generati...

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Bibliographic Details
Main Authors: Fernando M. Delgado-Chaves, Pedro Manuel Martínez-García, Andrés Herrero-Ruiz, Francisco Gómez-Vela, Federico Divina, Silvia Jimeno-González, Felipe Cortés-Ledesma
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Data in Brief
Subjects:
Topoisomerase inhibition
Differential gene expression
DNA supercoiling
Merbarone
RNA-Seq
Online Access:http://www.sciencedirect.com/science/article/pii/S235234092200693X

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http://www.sciencedirect.com/science/article/pii/S235234092200693X

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