A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia.

A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia.

We hypothesized that a common SNP in the 3' untranslated region of the upstream transcription factor 1 (USF1), rs3737787, may affect lipid traits by influencing gene expression levels, and we investigated this possibility utilizing the Mexican population, which has a high predisposition to dysl...

Full description

Bibliographic Details
Main Authors: Christopher L Plaisier, Steve Horvath, Adriana Huertas-Vazquez, Ivette Cruz-Bautista, Miguel F Herrera, Teresa Tusie-Luna, Carlos Aguilar-Salinas, Päivi Pajukanta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2730565?pdf=render

Internet

http://europepmc.org/articles/PMC2730565?pdf=render

Similar Items