Vesicular-Bound HLA-G as a Predictive Marker for Disease Progression in Epithelial Ovarian Cancer

Vesicular-Bound HLA-G as a Predictive Marker for Disease Progression in Epithelial Ovarian Cancer

Extracellular vesicles (EV) and their tumor-supporting cargos provide a promising translational potential in liquid biopsies for risk assessment of epithelial ovarian cancer (EOC) patients frequently relapsing, despite initial complete therapy responses. As the immune checkpoint molecule HLA-G, whic...

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Bibliographic Details
Main Authors: Esther Schwich, Vera Rebmann, Peter A. Horn, Alexander A. Celik, Christina Bade-Döding, Rainer Kimmig, Sabine Kasimir-Bauer, Paul Buderath
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
extracellular vesicles
vesicular-bound HLA-G
HLA-G<sub>EV</sub>
epithelial ovarian cancer (EOC)
liquid biopsy
platinum therapy
residual tumor burden
circulating tumor cells
Online Access:https://www.mdpi.com/2072-6694/11/8/1106

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https://www.mdpi.com/2072-6694/11/8/1106

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