LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b

LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b

Abstract Objective The exact mechanism and target molecules of liver fibrosis have remained largely elusive. Here, we investigated the role of long noncoding RNA Gm9866(lncRNA-Gm9866) on liver fibrosis. Methods The transcription of lncRNA-Gm9866 in activated cells and mouse fibrotic livers was deter...

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Bibliographic Details
Main Authors: Xiaomin Liao, Xianxian Ruan, Peishan Yao, Dan Yang, Xianbin Wu, Xia Zhou, Jie Jing, Dafu Wei, Yaodan Liang, Taicheng Zhang, Shanyu Qin, Haixing Jiang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
lncRNA
Gm9866
Liver fibrosis
Apoptosis
Fam98b
Online Access:https://doi.org/10.1186/s12967-023-04642-1

Internet

https://doi.org/10.1186/s12967-023-04642-1

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