The GDP-Mannose Dehydrogenase of <i>Pseudomonas aeruginosa</i>: An Old and New Target to Fight against Antibiotics Resistance of Mucoid Strains
Alginates play an important role in the resistance of mucoid strains of <i>Pseudomonas aeruginosa</i> to antibiotics, as well as their persistence by escaping the immune defense system. GDP-mannose dehydrogenase (GMD) is the key enzyme in alginate biosynthesis by catalyzing the irreversi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/12/1649 |