The GDP-Mannose Dehydrogenase of <i>Pseudomonas aeruginosa</i>: An Old and New Target to Fight against Antibiotics Resistance of Mucoid Strains

The GDP-Mannose Dehydrogenase of <i>Pseudomonas aeruginosa</i>: An Old and New Target to Fight against Antibiotics Resistance of Mucoid Strains

Alginates play an important role in the resistance of mucoid strains of <i>Pseudomonas aeruginosa</i> to antibiotics, as well as their persistence by escaping the immune defense system. GDP-mannose dehydrogenase (GMD) is the key enzyme in alginate biosynthesis by catalyzing the irreversi...

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Bibliographic Details
Main Author:	Christian Hulen
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Antibiotics
Subjects:	GDP-mannose dehydrogenase <i>Pseudomonas aeruginosa</i> mucoid strains enzymatic mechanism enzyme inhibitors
Online Access:	https://www.mdpi.com/2079-6382/12/12/1649

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