Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation

Abstract Severe COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in patients with COVID-19. To address these questions, we analyzed the metabolome of ne...

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Detalhes bibliográficos
Principais autores: Yafeng Li, Jessica S. Hook, Qing Ding, Xue Xiao, Stephen S. Chung, Marcel Mettlen, Lin Xu, Jessica G. Moreland, Michalis Agathocleous
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2023-05-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-023-37567-w