Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables
Background and Objective:Determination of HER2 gene is crucial in breast carcinoma management and prognosis, as HER2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal or...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iranian Society of Pathology
2017-01-01
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| Series: | Iranian Journal of Pathology |
| Subjects: | |
| Online Access: | https://ijp.iranpath.org/article_21544_3f5e90b80e6c212248854c76db8a92f4.pdf |