Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway

Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway

Abstract Background To investigate the treatment effect of vasoactive intestinal peptide (VIP) on osteoarthritis (OA) and the relative mechanism. Method The OA model on the SD rat knee was established using the modified Hulth method, and the recombinant pcDNA3.1+/VIP plasmid was constructed. One mon...

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Bibliographic Details
Main Authors: Yaozhong Liang, Shu Chen, Yuhao Yang, Chunhai Lan, Guowei Zhang, Zhisheng Ji, Hongsheng Lin
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Biomedical Science
Subjects:
Vasoactive intestinal peptide
Osteoarthritis
Synoviocytes
NF-κB signaling
Online Access:http://link.springer.com/article/10.1186/s12929-018-0410-z

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http://link.springer.com/article/10.1186/s12929-018-0410-z

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