Indazole–Quinolone Hybrids as Anti-Virulence Agents against <i>Pseudomonas aeruginosa</i>

Indazole–Quinolone Hybrids as Anti-Virulence Agents against <i>Pseudomonas aeruginosa</i>

Antibiotic resistance is a critical public health issue. Among the multi-drug resistant microorganisms in question, <i>Pseudomonas aeruginosa</i> has been designated by the WHO as a priority threat. Its virulence is orchestrated through quorum sensing (QS). This sophisticated communicati...

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Bibliographic Details
Main Authors: Marie Hanot, Marine Duplantier, Céline Dalle, Yani Ren, Sophie Da Nascimento, Jean-Paul Becker, Nicolas Taudon, Elodie Lohou, Pascal Sonnet
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Drugs and Drug Candidates
Subjects:
antibiotic resistance
<i>Pseudomonas aeruginosa</i>
quorum sensing
anti-virulence strategy
palladocatalyzed cross-coupling reactions
quinolone
Online Access:https://www.mdpi.com/2813-2998/3/3/30

Internet

https://www.mdpi.com/2813-2998/3/3/30

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